Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Moderately Good
Based on 66 Reviews
7.6
Supplement Facts
Serving Size:  3 Capsules
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine hydrochloride)
10 mg
588%
Magnesium (as magnesium aspartate, magnesium oxide)
435 mg
104%
Zinc (as zinc aspartate, zinc monomethionine, zinc oxide)
28 mg
255%

Top Medical Research Studies

9
Zinc protects heart function in OSA
We explored how zinc affects heart function in the context of obstructive sleep apnea (OSA), specifically focusing on cases of intermittent hypoxia (IH). In a detailed study using male rats, researchers set up different groups: a control group and one that underwent 10 weeks of exercise training. Half of the rats in both groups were exposed to IH conditions to simulate the effects of sleep apnea.

The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.

On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
Read More
7
Magnesium's role in sleep apnea
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
Read More

Most Useful Reviews

7.5
Improved sleep quality
29 people found this helpful
Gorgeous combination of zinc, magnesium, and vitamin B6! Optimum Nutrition's ZMA is essential for maximum recovery post-training. Zinc regulates cell growth and tissue repair, while magnesium maintains water-salt balance, generates energy, and normalises neuromuscular function. Exercising increases the need for these minerals, making ZMA a perfect supplement. Avoid taking ZMA with dairy or calcium supplements as it may reduce the anabolic effect and increase kidney stone risk. The effects are noticeably superior to other brands; I sleep like a baby on days I take it. My morning fatigue vanished with ZMA. I take 2 capsules before bedtime. Wishing you good health and a successful shopping experience on iHerb!
Read More
9
Enhanced muscle relaxation
22 people found this helpful
It certainly has an effect! I recommend it for serious sports enthusiasts. For casual exercisers, a standard multivitamin with B6, zinc, and magnesium might suffice. While I was quite active, I noticed significant improvements – my muscles were less tense, my sleep improved, and my digestion was smoother. Magnesium aids in bowel regularity, and these components also help in hormone regulation. For those who take a basic multivitamin, if you enjoy physical activity, I highly recommend trying ZMA for noticeable benefits.
Read More
7.5
Effective recovery aid
16 people found this helpful
Great ZMA complex! This combination of zinc, magnesium, and vitamin B6 is crucial for optimal recovery after workouts. Zinc supports cell growth and tissue repair, while magnesium aids in maintaining balance and energy production. The increase in mineral needs for active people makes ZMA ideal. Avoid dairy and calcium supplements with it, as this can diminish its anabolic effects and risk kidney stones. I find ZMA noticeably more effective than others; I sleep soundly when I take it. I now take 3 capsules before bed.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
  • All Researches
9
Zinc protects heart function in OSA
We explored how zinc affects heart function in the context of obstructive sleep apnea (OSA), specifically focusing on cases of intermittent hypoxia (IH). In a detailed study using male rats, researchers set up different groups: a control group and one that underwent 10 weeks of exercise training. Half of the rats in both groups were exposed to IH conditions to simulate the effects of sleep apnea.

The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.

On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
Read More
7
Magnesium's role in sleep apnea
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 66 Reviews
7.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Improved sleep quality
29 people found this helpful
Gorgeous combination of zinc, magnesium, and vitamin B6! Optimum Nutrition's ZMA is essential for maximum recovery post-training. Zinc regulates cell growth and tissue repair, while magnesium maintains water-salt balance, generates energy, and normalises neuromuscular function. Exercising increases the need for these minerals, making ZMA a perfect supplement. Avoid taking ZMA with dairy or calcium supplements as it may reduce the anabolic effect and increase kidney stone risk. The effects are noticeably superior to other brands; I sleep like a baby on days I take it. My morning fatigue vanished with ZMA. I take 2 capsules before bedtime. Wishing you good health and a successful shopping experience on iHerb!
Read More
9
Enhanced muscle relaxation
22 people found this helpful
It certainly has an effect! I recommend it for serious sports enthusiasts. For casual exercisers, a standard multivitamin with B6, zinc, and magnesium might suffice. While I was quite active, I noticed significant improvements – my muscles were less tense, my sleep improved, and my digestion was smoother. Magnesium aids in bowel regularity, and these components also help in hormone regulation. For those who take a basic multivitamin, if you enjoy physical activity, I highly recommend trying ZMA for noticeable benefits.
Read More
7.5
Effective recovery aid
16 people found this helpful
Great ZMA complex! This combination of zinc, magnesium, and vitamin B6 is crucial for optimal recovery after workouts. Zinc supports cell growth and tissue repair, while magnesium aids in maintaining balance and energy production. The increase in mineral needs for active people makes ZMA ideal. Avoid dairy and calcium supplements with it, as this can diminish its anabolic effects and risk kidney stones. I find ZMA noticeably more effective than others; I sleep soundly when I take it. I now take 3 capsules before bed.
Read More
9
Quick effectiveness
8 people found this helpful
Great product! I hesitated to buy it but am now glad I did. This dietary supplement truly works. Although I didn’t take it on an empty stomach, I felt results in just 10-15 minutes. I sleep very well now, waking up refreshed without the heaviness typical of sleeping pills. I definitely recommend it for anyone struggling with sleep.
Read More
7.5
Promotes deep sleep
8 people found this helpful
Excellent complex! ZMA is vital for optimal recovery after intense training. It combines zinc, magnesium, and vitamin B6, important for cell repair and immune health. Magnesium aids in water-salt balance and energy, which increases with exercise. ZMA should not be taken with dairy or calcium, as this can reduce its effects and risk kidney stones. I find the effects much stronger than other products; I sleep deeply when I use it. It significantly helps my morning fatigue; I take 3 capsules before bed.
Read More

Frequently Asked Questions

9
Quick effectiveness
8 people found this helpful
Great product! I hesitated to buy it but am now glad I did. This dietary supplement truly works. Although I didn’t take it on an empty stomach, I felt results in just 10-15 minutes. I sleep very well now, waking up refreshed without the heaviness typical of sleeping pills. I definitely recommend it for anyone struggling with sleep.
9
Solved sleep issues
1 people found this helpful
Prior to taking this supplement after intense training, I struggled with sleep issues. It became evident that I lacked zinc or magnesium. After starting this combined complex, I resolved my sleep problems in just two doses, and they haven’t returned in a year.
9
Increased energy
1 people found this helpful
It helps me achieve a calm sleep, leading to more energy at the gym and fewer muscle spasms. Taking these caps an hour before sleep, with plenty of liquid, makes me very sleepy within 30 minutes. I wake up relaxed and not groggy. After about 3 months of use, I've noticed a leaner appearance and weight loss.
9
Recovery aid
1 people found this helpful
ZMA has been superb for me over the years. I use it to recover after hard workouts and to help me sleep through the night without interruptions. Combining it with Gold Standard 100% Casein maximises its benefits.
9
Sustained energy boost
5 people found this helpful
This product is simply amazing! I often work late, and it really helps me get quality sleep even after long nights. I wake up alert without feeling tired. It has definitely improved my energy levels throughout the day! I highly recommend this product for anyone needing sustained energy.
9
Quality sleep
1 people found this helpful
I sleep like a baby. This product helps me achieve quality sleep, calms me, and allows me to stay asleep without waking groggy in the mornings. Absolutely love it!
7.5
Improved sleep quality
29 people found this helpful
Gorgeous combination of zinc, magnesium, and vitamin B6! Optimum Nutrition's ZMA is essential for maximum recovery post-training. Zinc regulates cell growth and tissue repair, while magnesium maintains water-salt balance, generates energy, and normalises neuromuscular function. Exercising increases the need for these minerals, making ZMA a perfect supplement. Avoid taking ZMA with dairy or calcium supplements as it may reduce the anabolic effect and increase kidney stone risk. The effects are noticeably superior to other brands; I sleep like a baby on days I take it. My morning fatigue vanished with ZMA. I take 2 capsules before bedtime. Wishing you good health and a successful shopping experience on iHerb!
9
Quality of sleep
1 people found this helpful
Excellent! I’ve tried it multiple times, and taking 3 tablets before bed significantly enhances my sleep quality.
9
Excellent for insomnia
2 people found this helpful
The packaging and quality of this product are impressive. I'm sure it works well for those who go to the gym or suffer from insomnia, as it helps one achieve a deep sleep. The dosage is clear: three pills for men and two for women, taken two hours before bed.
7.5
Effective recovery aid
16 people found this helpful
Great ZMA complex! This combination of zinc, magnesium, and vitamin B6 is crucial for optimal recovery after workouts. Zinc supports cell growth and tissue repair, while magnesium aids in maintaining balance and energy production. The increase in mineral needs for active people makes ZMA ideal. Avoid dairy and calcium supplements with it, as this can diminish its anabolic effects and risk kidney stones. I find ZMA noticeably more effective than others; I sleep soundly when I take it. I now take 3 capsules before bed.
7
Magnesium's role in sleep apnea
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
9
Zinc protects heart function in OSA
We explored how zinc affects heart function in the context of obstructive sleep apnea (OSA), specifically focusing on cases of intermittent hypoxia (IH). In a detailed study using male rats, researchers set up different groups: a control group and one that underwent 10 weeks of exercise training. Half of the rats in both groups were exposed to IH conditions to simulate the effects of sleep apnea.

The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.

On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.

References

  1. Luo X, Tang M, Wei X, Peng Y. Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study. J Affect Disord. 2024;358:105. doi:10.1016/j.jad.2024.05.002
  2. Chen TI, Chen MY. Zinc Is Indispensable in Exercise-Induced Cardioprotection against Intermittent Hypoxia-Induced Left Ventricular Function Impairment in Rats. PLoS One. 2016;11:e0168600. doi:10.1371/journal.pone.0168600
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